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June 15, 2010

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Alan Beall

I thought you would be interested in this.

http://articles.mercola.com/sites/articles/archive/2010/06/22/some-protein-drinks-could-poison-you.aspx

I know Mercola is trying to sell his product, and his is only the best, blah, blah, but there may be something in here that will be of interest to you. The part I'm concerned about is how the cow was fed and pasteurization. To quote from the article:

Most commercial whey products are derived from pasteurized dairy and processed with heat and acid. Many are also artificially sweetened. All of these factors render them completely useless from a health perspective.

Whey from organic grass-fed dairy, on the other hand, contains beneficial immuno components, including immunoglobins, bovine serum albomin, and lactoferins, in addition to all the key amino acids and other beneficial nutrients you typically get from a high quality whey protein.*

Integrated Supplements

Much of the information from Dr Mercola's article is demonstrably false - pasteurized dairy is not completely useless from a health perspective - that is, if selective filters are used to rid the end product (whey protein) of the proteins which are denatured in pasteurization. This is exactly the process employed in the production of the CFM. Dr Mercola is right that most protein powders are damaged in processing, but this isn't true of all of them. We've got documentation, based on nitrogen solubility testing, that CFM contains greater than 97% undenatured whey protein. I'm not sure if Dr Mercola is claiming that his product comes from unpasteurized milk (I highly doubt that it is), but even if it were, it wouldn't necessarily make any difference -he would have to provide nitrogen solubility testing to prove that it was, indeed, undenatured.

Along these same lines, CFM, containing the highest levels of undenatured proteins, will contain immunoglobulins, bovine serum albumin, and lactoferrin, etc - which are not a function of grass feeding as Mercola states. Grass feeding can alter the lipid composition of milk (perhaps negatively, by the way), but the protein structures / composition don't seem to be altered by grass feeding. Again, testing of the final product is what's needed, but Dr. Mercola doesn't seem to provide the results of testing - he merely plays into the positive associations people have with the terms such as grass-fed and organic, etc.

Also note that a serving of the product being promoted in the Doctors article will contain 40 mg of cholesterol per serving as a result of the relatively inefficient processing
technique employed in the production of whey protein concentrate. As you may have read in some of our articles, the scientific literature gives every reason to believe that cholesterol in powdered form is prone to oxidation, and is therefore atherogenic (causing hardening of the arteries / heart disease). This point is of meaningful significance, but is conspicuously absent from Dr. Mercola's writings on whey protein.

One of the things we do in our newsletters and blog posts is link directly to the relevant scientific articles so that our readers can see for themselves that what we are saying is
backed up by the scientific literature. One of the things that's so frustrating about much of the health writing on the internet is that people often make statements which aren't backed up by the findings in the scientific literature, but because people promote themselves as health experts, many people believe what these people say in the absence of evidence. Because of my research in the field of dairy chemistry, it's easy for me to see how intellectually-sloppy and short-sighted most experts' understanding of whey protein is. Unfortunately, many people take it upon themselves to widely disseminate these mistaken assumptions.

Oh well, thats what we're here for, I guess. If you've got any other questions, or need any clarification, just let me know - I'd be happy to help.

Alan Beall

It's interesting that you bring up the issue of oxidixed cholesterol because that's how I found you in the first place. I googled "oxidized cholesterol powdered milk" and your blog came up. I ended up reading your articles on whey, fiber and creatine and ordered all three. What I appreciated the most was your careful analyses based on studies that were not only quoted but also linked. As I remember, you also linked to articles that had opposing views so that I could analyze the evidence for myself. This did nothing but add to your credibility.

As a non-scientist with no chemistry background, I have a tendency to be impressed with those that explain things in chemical terms. Experience has taught me that I have to be on guard against anyone that throws around data that I only have a partial understanding of. When a scientist presents only one side of the story, chances are better than even that I won't even know that a second side exists. I am constantly finding circles within circles within circles, and it is very difficult to assess what is true. "Grass feeding can alter the lipid composition of milk (perhaps negatively, by the way) " is a good example. So far, I have only heard about the positive effects of grass-feeding as it pertains to lipids. Would it be too much to ask you to send me a link to that info?

Thanks again for your thoughtful reply.

Integrated Supplements

Hi Alan,

I’m glad you enjoy the fact that we link to the research – it takes quite a bit of time and effort to construct our articles that way so I’m always happy to hear that people find it useful.

A few weeks ago, I came across an article snippet telling of a study which found that people who ate grain-fed beef experienced better changes in their lipid profile (higher HDL and larger LDL-particle size) relative to those who ate pasture- or grass-fed beef. I did a little searching when you asked, and came up with the following article which comments on the research:

http://agnews.tamu.edu/showstory.php?id=1934

I don’t know if the study, itself, has been published yet.

Of course, based upon the findings outlined in the article, or even the study itself, I don’t think we can necessarily make any firm conclusions as to which type of beef is better health-wise, but I do think it speaks to the fact that oftentimes the research can get us to start asking more meaningful questions. If grain-fed beef is associated with a more favorable lipid profile, is this effect long-lasting? What are the differences in grain-fed versus grass-fed beef which account for the effects?

To be clear, I don’t think that grass-fed beef is detrimental in any way, I was simply trying to point out that the effects of different feeds on the lipid composition of beef (and milk), and the effect of these lipids on human health is currently an area of intense research. I suspect that many of the assumptions people (researchers included) have with regard to what constitutes “healthy fats” will change significantly as this research continues. There are simply a lot of details that haven’t been figured out yet.

You stated it perfectly – as a person trying to understand nutrition research, you may often only hear one side of the story, and never even know another side exists.

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  • * No Integrated Supplement product is intended to treat, diagnose, prevent, or cure any disease. Though the research presented sometimes references disease states, this research is meant to elucidate the function of nutrients, and is not meant to imply that any nutrients or foods can act to treat, prevent, or cure such diseases.

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